Diet and nutritionIs losing weight a matter of willpower? Why this may be a big lie
- prof. David Ludwig — How Hunger Works: A Brief Conversation on the Science of Metabolism
- prof. David Ludwig — Is Weight Loss Just a Matter of Will Power?
- prof. David Ludwig — Why Calorie Restricted Diets Don’t Work
- Bracia Rodzeń — Bracia Rodzeń
- Self-directed interventions to promote weight loss: a systematic review and meta-analysis. · Health Psychol Rev 2016
- Behavioral and Psychological Factors Affecting Weight Loss Success. · Curr Obes Rep 2023
- Autonomy support, self-regulation, and weight loss. · Health Psychol 2014
- Self-control and grit: associations with weight management and healthy habits. · J Behav Med 2024
- Personality Traits and Weight Loss Surgery Outcome. · Curr Obes Rep 2018
- Long-term weight loss maintenance. · Am J Clin Nutr 2005
- Silencing the Sirens: Weight-Loss Drugs, Food Noise, and the Ethics of Effortless Self‑Control. · J Med Humanit 2026
- Intervention Effectiveness for Self-Efficacy to Control Eating among Women with Obesity in the Atlanta Area. · Health Soc Work 2026
- Adherence and weight loss with a total diet replacement programme for increased cancer risk associated with obesity: a UK cohort study. · BMJ Open 2026
- Behavioral Factors Associated With ≥ 15% Versus < 5% Weight Loss in Adults With Severe Obesity: A Retrospective Clinical Study. · Obes Sci Pract 2026
- Orthomolecular Medicine News Service — GLP-1 Receptor Agonists and Vitamin C: A Powerful Anti-Aging Combination
- Orthomolecular Medicine News Service — Plenty of Food but not Plenty of Weight
- Orthomolecular Medicine News Service — GLP-1 Weight-Loss Drugs and Optic Nerve Risks: What Clinicians and Patients Should Know
Prof. David Ludwig says that losing weight does not depend mainly on willpower, because hunger can be stronger than it.
- Prof. David Ludwig adds that obesity is more closely linked to biology than to willpower, so you should not blame yourself.
- Bracia Rodzeń mention that doctors blamed patients and told them they were not losing weight because they lacked willpower.
- Prof. David Ludwig also describes biological responses that can make changes in body weight difficult and defend its previous level.
What the authors write
Hunger is a biological response that can be stronger than willpower.
Obesity is more closely linked to biology than to willpower, but you can adapt your actions to your biology.
Biological responses can make significant changes in body weight difficult and push it back toward its previous level.
Bracia Rodzeń mention that doctors told patients they could not lose weight because they lacked willpower.
Research from PubMed · Europe PMC
We selected 10 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 3 912.
A meta-analysis found that self-directed weight-loss programs can lead to moderate weight loss, although maintaining the results may require additional support.
Aim of the study: Many self-directed weight-loss interventions have been developed using a variety of delivery formats (e.g., internet and smartphone) and change techniques. Yet, little research has examined whether self-directed interventions can exclusively promote weight loss.
Results: Twenty-seven trials incorporating 36 comparisons met our inclusion criteria. Participants using self-directed interventions lost significantly more weight (MD = -1.56 kg, CI -2.25, -0.86 ranging from 0.6 to 5.3 kg) compared to those in the minimal intervention or no-treatment groups (3.1-month follow-up median). The majority of interventions were internet based (18 evaluations) and these were effective at 3 months (MD = -1.74 kg, CI -2.65, -0.82 ranging from 0.6 to 4.8 kg) (SMD = -0.48, 95% CI -0.72, -0.24, I(2) = 82%; p < .0001; 16 evaluations) and 6 months follow-up (MD = -2.71 kg, CI -4.03, -1.39 ranging from 2.2 to 5.3 kg) (SMD = -0.59, 95% CI -0.99, -0.19, I(2) = 76%; p = .004; 4 evaluations). Self-directed weight-loss interventions can generate modest weight loss for up to 6 months but may need to be supplemented by other interventions to achieve sustained and clinically meaningful weight loss.
“Not stated” does not mean nobody paid — the database does not always record it.
The review suggests that weight-loss success depends on many psychological and behavioral factors, not just biology.
Aim of the study: There is a large variability between individuals in the weight loss response to any given diet treatment, which fuels interest into personalized or precision nutrition. Although most efforts are directed toward identifying biological or metabolic factors, several behavioral and psychological factors can also be responsible for some of this interindividual variability.
Results: There are many factors that can influence the response to dietary weight loss interventions, including factors related to eating behavior (emotional eating, disinhibition, restraint, perceived stress), behaviors and societal norms related to age and sex, psychological and personal factors (motivation, self-efficacy, locus of control, self-concept), and major life events. The success of a weight loss intervention can be influenced by many psychological and behavioral constructs and not merely by physiological factors such as biology and genetics. These factors are difficult to capture accurately and are often overlooked. Future weight loss studies should consider assessing such factors to better understand the underlying reasons for the large interindividual variability to weight loss therapy.
“Not stated” does not mean nobody paid — the database does not always record it.
The study found that autonomy support was associated with greater weight loss, while some forms of directive support could hinder progress.
Aim of the study: Social support is believed to contribute to weight loss success, yet the type of support received is rarely assessed. To develop more effective weight loss interventions, examinations of the types of support that are associated with positive outcomes are needed. Self-Determination Theory suggests that support for an individual's autonomy is beneficial and facilitates internalization of autonomous self-regulation.
Results: Baseline AS and ASR did not predict outcomes; however, AS and ASR at 6 months positively predicted 18-month weight losses (ps < .05), encouragement of healthy eating at 6 months was negatively related to 18-month weight losses (p < .01), and other forms of directive support were not associated with outcomes. Autonomy support predicted better weight loss outcomes while some forms of directive support hindered progress. Weight loss trials are needed to determine whether family members and friends can be trained to provide autonomy support and whether this is more effective than programs targeting more general or directive forms of support.
“Not stated” does not mean nobody paid — the database does not always record it.
Increased self-control and perseverance were associated with developing habits that support weight management, while baseline perseverance was associated with maintaining weight loss.
Aim of the study: Weight management requires resisting immediate temptations in one's environment (self-control) as well as the ability to persevere towards one's long-term goals despite minor setbacks (grit). This study sought to establish relationships between self-control, grit, and behavioral and health outcomes in the context of a couples-based weight management intervention.
Results: Baseline self-control, changes in self-control, and baseline grit were also associated with 6-month exercise automaticity. Only baseline grit was associated with weight loss maintenance. No partner effects were observed. Findings suggest that self-control and grit are malleable constructs that may play an important role in health behavior habits associated with weight management.ClinicalTrials.gov: NCT02570009, October, 7, 2015.
“Not stated” does not mean nobody paid — the database does not always record it.
The review found that the ability to self-regulate despite momentary temptations was linked to better outcomes after bariatric surgery.
Aim of the study: To update the recent findings on the influence of personality features on postoperative weight loss in patients undergoing bariatric surgery.
Results: Several studies investigated the influence of pre-surgical psychological variables on the outcome of bariatric surgery, but the effective role of personality factors (i.e., both normal personality traits and personality disturbances) in shaping bariatric surgery outcome is still unclear. We analyzed nine recent papers that examined the impact of pre-operative personality traits on postoperative weight loss among individuals undergoing surgery for severe obesity. A personality pattern denoting the ability to self-regulate in spite of the urges or demands of the moment emerged as a robust predictor of good outcome across studies, independently from baseline psychiatric comorbidity and personality disorders.
“Not stated” does not mean nobody paid — the database does not always record it.
The review suggests that long-term weight loss maintenance is possible, and that success is associated with consistent habits such as physical activity and weight monitoring.
Aim of the study: There is a general perception that almost no one succeeds in long-term maintenance of weight loss. However, research has shown that approximately 20% of overweight individuals are successful at long-term weight loss when defined as losing at least 10% of initial body weight and maintaining the loss for at least 1 y.
Results: To maintain their weight loss, members report engaging in high levels of physical activity ( approximately 1 h/d), eating a low-calorie, low-fat diet, eating breakfast regularly, self-monitoring weight, and maintaining a consistent eating pattern across weekdays and weekends. Moreover, weight loss maintenance may get easier over time; after individuals have successfully maintained their weight loss for 2-5 y, the chance of longer-term success greatly increases. Continued adherence to diet and exercise strategies, low levels of depression and disinhibition, and medical triggers for weight loss are also associated with long-term success. National Weight Control Registry members provide evidence that long-term weight loss maintenance is possible and help identify the specific approaches associated with long-term success.
“Not stated” does not mean nobody paid — the database does not always record it.
The article argues that obesity should not be reduced to weak willpower, and that effective control of behavior does not necessarily have to feel effortful.
Aim of the study: Drawing upon firsthand accounts of GLP-1RA weight-loss drugs, this paper challenges the bioconservative view that effort is essential to self-control and the narrower view that obesity is simply a matter of weakness of will. Many dieters have persistent intrusive food thoughts that are neither transparent nor voluntarily controllable.
Results: Many dieters have persistent intrusive food thoughts that are neither transparent nor voluntarily controllable. By quieting food noise, these drugs offer users epistemic access to the true target of effective self-control and provide a pathway to long-term success that effort alone rarely secures. We argue that the value of self-control lies not in the subjective experience of struggle but in the skillful alignment of behavior with one's goals. "Effortless" self-control, far from being a cheat, can exemplify precisely what is valuable about agency.
“Not stated” does not mean nobody paid — the database does not always record it.
An increased sense of being able to control eating predicted later changes in body weight.
Aim of the study: Behavioral obesity treatments are associated with early weight loss; however, participants typically begin to regain the weight within several months as their self-efficacy to control eating (SEce) often diminishes after they begin to better realize associated challenges. Therefore, authors of this article aimed to discern psychosocial predictors of such reductions.
Results: There was no significant time × treatment type effect. Within multiple regression analyses, each of those correlates, except dejection, significantly contributed to the explained variance in SEce change (p < .001). Participants' change in SEce from baseline to Month 6 was a significant predictor of their six-, 12-, and 24-month weight changes (ps < .001). These findings suggest psychosocial targets for addressing decreases in SEce and subsequent regains in weight that can follow.
“Not stated” does not mean nobody paid — the database does not always record it.
Participants in the meal-replacement program lost weight on average, based on the median, and some of the weight loss was maintained after a year.
Aim of the study: To evaluate engagement and weight loss with a 12-month total diet replacement (TDR) programme in women with increased risk of breast and endometrial cancer, living with obesity.
Results: 37 women (79%) completed the whole programme. Completers and those who withdrew, respectively, had a mean (SD) age of 41.4 years (5.7) vs 38.1 (5.8) and baseline body mass index of 36.2 (4.9) kg/m2 vs 40.0 (7.9) kg/m2 and 76% vs 90% had children 18 or younger living at home. Median (IQR) weight was reduced at all time points; -10.8 kg (-13.8, -7.2) at 3 months, -11.5 kg (-15, -7.6) at 6 months, -11.0 kg (-16.4, -7.8) at 9 months and -8.4 kg (-13.9, -3.7) at 12 months. Across the 12-month programme, the median (IQR) contacts with the study dietitians per participant was 28 (25, 33) and median contact hours were 7.6 (6.6, 10.6). 68% received psychological support. QOL improved; OWL-QOL (Obesity and Weight Loss)-17 (-24.8, -7.8) and EQ5D 1 (0, 2), with reductions in binge eating scores -4 (-6.5, -0.8) but no changes in mental health or physical activity scales. TDR could be a weight loss programme for women at increased risk of breast and endometrial cancers related to obesity.
“Not stated” does not mean nobody paid — the database does not always record it.
Greater weight loss during the program was associated with more frequent use of several dietary and physical activity strategies.
Aim of the study: Sustained weight loss requires a persistent reduction in energy intake combined with increased energy expenditure. Assessment of such strategies can improve treatment outcomes. The National Weight Control Registry (NWCR) has identified behavioral approaches associated with successful long-term weight loss maintenance.
Results: Participants achieving ≥ 15% WL more frequently reported reduced energy intake, reduced fat and sugar consumption, and regular physical activity at both 6 and 12 months compared with those achieving < 5% WL (all p < 0.03). Individuals in the ≥ 15% WL group reported a greater number of successful strategies at both time points (p < 0.001). These findings from a clinical setting largely corroborate previous registry-based evidence, demonstrating that clinically significant weight loss achieved during structured obesity treatment is associated with more frequent reporting of behaviors identified by the National Weight Control Registry.
“Not stated” does not mean nobody paid — the database does not always record it.
Perspectives and opinion materials
The content below presents the authors’ opinions, interpretations and hypotheses. It is not treated as equal to scientific studies and systematic reviews.
Pisaczek does not judge who is right. It shows what was written and where to read it. Every sentence above has its source.