Vitamins and mineralsVitamin U — cabbage juice for stomach ulcers?
- Henryk Różański — Witamina U
- Henryk Różański — Rośliny krzyżowe Cruciferae a tarczyca
- Henryk Różański — Brokuły – Brassicas oleracea varium botrytis subvarium cymosa Lam.
- Henryk Różański — Burak czerwony – Beta vulgaris var. esculenta
- Rapid healing of peptic ulcers in patients receiving fresh cabbage juice. · Calif Med 1949
- S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers. · Pharmaceuticals (Basel) 2026
Henryk Różański describes cabbage juice as a natural source of vitamin U, which was believed to have anti-ulcer properties.
- Vitamin U was believed to speed up healing and dry out ulcers, as well as relieve gastritis and excessive secretion of gastric juice.
- Henryk Różański criticizes the taste and composition of the Polish sauerkraut juices he has bought.
What the authors write
Vitamin U occurs naturally in cabbage juice and was considered an anti-ulcer remedy.
Vitamin U was believed to speed up the healing of ulcers and dry them out, relieve the symptoms of gastritis, and inhibit excessive secretion of gastric juice.
Cabbage juice was described as a source of vitamin U with anti-ulcer properties.
Broccoli was also described as a source of vitamin U with anti-ulcer properties.
Henryk Różański described the Polish sauerkraut juices he had bought as terrible in taste and composition.
Research from PubMed · Europe PMC
We selected 2 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 1.
In 13 patients treated with fresh cabbage juice, ulcers healed faster than the times reported for standard treatment.
Aim of the study: Thirteen patients with peptic ulcer were treated with fresh cabbage juice, which, experiments have indicated, contains an antipeptic ulcer factor. This factor (vitamin U) prevents the development of histamin-induced peptic ulcers in guinea pigs.
Results: This factor (vitamin U) prevents the development of histamin-induced peptic ulcers in guinea pigs. The average crater healing time for seven of these patients who had duodenal ulcer was only 10.4 days, while the average time as reported in the literature, in 62 patients treated by standard therapy, was 37 days. The average crater healing time for six patients with gastric ulcer treated with cabbage juice was only 7.3 days, compared with 42 days, as reported in the literature, for six patients treated by standard therapy. The rapid healing of peptic ulcers observed radiologically and gastroscopically in 13 patients treated with fresh cabbage juice indicates that the anti-peptic ulcer dietary factor may play an important role in the genesis of peptic ulcer in man.
“Not stated” does not mean nobody paid — the database does not always record it.
The review describes the protective and anti-ulcer effects of S-methylmethionine, but notes that clinical data in humans are limited.
Aim of the study: S-methylmethionine (SMM, also known as vitamin U) is a sulfur-containing vitamin-like compound that has been investigated since the 1940s for its gastroprotective and cytoprotective properties. Historically derived from observations of antiulcer activity in plant-derived foods, SMM has been studied in preclinical models and limited clinical settings for its multilevel pharmacological effects.
Results: Proposed mechanisms are mediated primarily through suppression of oxidative stress, modulation of inflammatory and immune responses, maintenance of glutathione homeostasis, activation of ERK/NF-κB and Nrf2/Keap1 pathways, and regulation of methylation processes. Building on recent descriptive reviews, this work provides a structured critical synthesis that grades evidence quality, compares SMM with the structurally related methyl donor S-adenosylmethionine (SAMe), and analyses the translational and regulatory barriers that have prevented Western drug registration despite over 70 years of investigation. Despite a substantial preclinical evidence base and historical clinical observations, the level of evidence for many indications remains limited. Well-designed Phase II randomized controlled trials and innovative pharmaceutical formulations (especially topical and mucosal delivery systems) are urgently needed to translate preclinical promise into clinical benefits.
“Not stated” does not mean nobody paid — the database does not always record it.
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