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Diseases

Cavitations in the jawbone — hidden sites of inflammation after tooth extraction?

Sources: 7 · Article: 13 127 characters

Igor Dogocki links cavitations in the upper and lower jawbones to extraction wounds that do not heal optimally.

  • According to him, ordinary X-rays are not enough to detect them, and substances associated with symptoms outside the mouth may form at cavitation sites.
  • Dogocki lists chronic fatigue, joint pain, migraines, and difficulty concentrating among the possible effects.
  • Nathan S. Bryan encourages people with symptoms and a history of tooth extraction to consider having their jawbone examined with a 3D scan by a biological dentist.

What the authors write

Igor Dogocki

Cavitations are changes in the upper and lower jawbones that Igor Dogocki describes as fatty degenerative osteolysis.

„Few people know that these problems may also originate in the mouth—especially when oral hygiene and teeth appear flawless at first glance. A closer look often brings clarity: many people have what are known as fatty degenerative osteolyses in the upper and lower jawbones (FDOJ—cavitations).”Niewielu wie, że te dolegliwości mogą mieć przyczynę również w jamie ustnej – zwłaszcza gdy stan higieny i zębów na pierwszy rzut oka wydaje się nienaganny. Drugie, bliższe spojrzenie często przynosi jasność: u wielu osób występują tzw. tłuszczowe degeneracyjne osteolizy w kościach szczęki i żuchwy (FDOK – kawitacje).
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki links cavitations, among other things, to extraction wounds that do not heal optimally.

„Cavitations are caused by a weakened immune system and result from extraction wounds, tooth buds, and foreign bodies in the bone that do not heal optimally. Above all, however, they indicate a lack of vitamins, minerals, and trace elements needed during bone formation and maturation/remodeling.”Kawitacje spowodowane są osłabionym układem odpornościowym, powstają w wyniku niegojących się optymalnie ran po ekstrakcji zębów, zawiązków zębów oraz obecności w kości ciał obcych. Niemniej jednak przede wszystkim świadczą o braku witamin, minerałów i pierwiastków śladowych, których zabrakło w procesie tworzenia i dojrzewania/modelowania się kości.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki says that FDOJ usually cannot be seen on standard X-rays and that these images are not sufficient for diagnosis.

„Above all, however, they indicate a lack of vitamins, minerals, and trace elements needed during bone formation and maturation/remodeling. FDOJ (cavitations) are usually not visible on conventional X-rays. This refers to standard 2D and 3D X-rays, which provide an initial overview but are not sufficient to diagnose FDOJ.”Niemniej jednak przede wszystkim świadczą o braku witamin, minerałów i pierwiastków śladowych, których zabrakło w procesie tworzenia i dojrzewania/modelowania się kości. FDOK (kawitacje) zwykle nie są widoczne na klasycznym, konwencjonalnym zdjęciu rentgenowskim. Mamy na myśli tu standardowe zdjęcia rentgenowskie 2D i 3D, które zapewniają wstępny przegląd, ale nie są wystarczające do zdiagnozowania FDOK.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki says that toxins and inflammatory mediators form at cavitation sites and may be associated with symptoms outside the mouth.

„As with dead teeth, toxins and inflammatory mediators (TNF-α, IL-1, RANTES, or CCL-5) form at cavitation sites and may cause a range of symptoms elsewhere in the body—neurological problems and joint inflammation are particularly common.”Podobnie jak w przypadku martwych zębów, w miejscach kawitacji powstają toksyny i mediatory stanu zapalnego (TNF-α, IL-1, RANTES, czyli CCL-5), które mogą powodować różnorodne objawy w innych częściach ciała – szczególnie częste są problemy neurologiczne lub stany zapalne w stawach.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki assigns the cytokine RANTES an important role in inflammatory processes and lists diseases associated with elevated RANTES.

„In FDOJ, the cytokine RANTES (CCL-5) plays a dominant role. Elevated RANTES levels may be found in joint inflammation or rheumatoid arthritis, multiple sclerosis, certain types of breast cancer, Parkinson’s disease, and Alzheimer’s disease.”W FDOK cytokiny RANTES (CCL-5) odgrywają dominującą rolę. Podwyższone wartości RANTES można zaobserwować w stanach zapalnych stawów lub reumatoidalnym zapaleniu stawów, stwardnieniu rozsianym, niektórych typach raka piersi, chorobie Parkinsona i chorobie Alzheimera.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki lists chronic fatigue, joint pain, migraines, and difficulty concentrating as possible effects of FDOJ.

„Other possible effects of FDOJ include: autoimmune diseases (e.g., rheumatism) joint pain (in the limbs, back, and face) lack of energy (burnout) migraines and difficulty concentrating chronic weakness (chronic fatigue syndrome) small intestine problems multiple sclerosis.”Inne możliwe skutki FDOK to: choroby autoimmunolo giczne (np. reumatyzm) bóle stawów (kończyn, ple ców i twarzy) brak energii (wypalenie) migreny i trudności z kon centracją chroniczne osłabienie (zespół chronicznego zmęczenia) problemy z jelitem cienkim stwardnienie rozsiane.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki describes the surgical removal of diagnosed cavitations and claims that new bone can form at the site with the help of stem cells.

„Identified cavitations are surgically removed using a special pro-immune protocol. With the help of stem cells, new, healthy bone forms in the previously infected area. If you have chronic diseases or illnesses with no clear cause, consider immunological dentistry and the appropriate removal of all interference fields from the mouth.”Zidentyfikowane kawitacje zostają odpowiednio usunięte chirurgicznie w specjalnym, pro immunologicznym protokole. Z pomocą komórek macierzystych powstaje we wcześniej zainfekowanym miejscu nowa, zdrowa kość. W przypadku występowania chorób przewlekłych i chorób niemających jasnej przyczyny pomyśl o stomatologii immunologicznej i odpowiednim usunięciu z jamy ustnej wszystkich pól interferencyjnych.
Usuwanie FDOK kawitacji
Igor Dogocki

Igor Dogocki says that treatments for chronic diseases often begin to work only after sites of inflammation and toxic substances are removed from the mouth.

„This is because treatments for chronic diseases often begin to work only after sites of inflammation and toxic substances are removed from the mouth. If you are at a standstill and your treatments are not as effective as you expect, and your body is rebelling and it is hard to regain your health, think of yourself as a computer.”Dzieje się tak, ponieważ terapie chorób przewlekłych często zaczynają działać dopiero po usunięciu ognisk zapalnych i toksycznych substancji z jamy ustnej. Jeśli jesteś w martwym punkcie i terapie, które stosujesz, nie są tak skuteczne, jak oczekujesz, a organizm strajkuje i ciężko jest dojść do pełni zdrowia, pomyśl o sobie jak o komputerze.
Usuwanie FDOK kawitacji
Nathan S. Bryan

Nathan S. Bryan encourages people with symptoms to consider the possibility of infection, take previous tooth extractions into account, and have their jawbone examined with a 3D scan by a biological dentist.

„Instead, ask yourself whether you might have an infection. Have you ever had a root canal? Have you had your wisdom teeth or any other tooth extracted? Instead of seeing a medical specialist or an oncologist if you have cancer, see a really good biological dentist who has a 3D cone-beam CT scanner to visualize your jawbone.”Instead ask yourself if you may have an infection. Have you ever had a root canal? Did you have your wisdom teeth or any other tooth extracted? Instead of going to a physician specialist or an oncologist if you have cancer, go see a really good biological dentist who has a 3D cone beam CT scan to visualize your jaw bone.
Root Canals

Research from PubMed · Europe PMC

We selected 5 studies with the best, positive results. This is a selection, not a full review of all research.

Total number of studies on this topic in PubMed: 1.

In the study, bone density increased in most treated lesions, and the number of lesions per patient decreased after therapy.

Aim of the study: This study evaluated the possibility of using NeuroModulation Technique (NMT), a form of intention-based medicine, to induce osteogenesis and healing of cavitational osteonecrosis, a common progressive form of ischemic disease of the alveolar arch.

Results: At the first scan, all subjects had between one and six cavitational lesions, most of which (92%) were associated with sites of previous tooth extraction. Patients treated with NMT showed a significant improvement in bone density in 27 of the 34 lesions analyzed (79%). The median number of lesions per patient was 4 before treatment and 0 after treatment (p < 0.01). One patient treated with NMT, one patient treated surgically, and the control subject were also imaged at later time points. The images showed lasting healing of the lesions with NMT, comparable to that achieved with surgery, while the disease persisted in the untreated control. NMT therapy offers a safe and potentially effective treatment for jawbone osteonecrosis. Preclinical placebo-controlled trials are encouraged to investigate the potential of NMT for treating inflammatory and degenerative conditions in depth.

Resolution of cavitational osteonecrosis through NeuroModulation Technique, a novel form of intention-based therapy: a clinical case study. · J Altern Complement Med 2009
Money for the studynot stated
Do the authors have ties to companies?not stated
Did a manufacturer help with the study?unknown
Type of studyclinical study in people
Participants11

“Not stated” does not mean nobody paid — the database does not always record it.

Treatment, particularly surgery on jawbone lesions, was associated with a decrease in blood RANTES/CCL5 levels.

Aim of the study: The presence of bone marrow defects of the jawbone (BMDJ) is associated with increased levels of inflammatory cytokines such as RANTES/CCL5. The purpose of this study was to analyze whether BMDJ therapy under real-world conditions reduces serum RANTES/CCL5 levels in patients with BMDJ.

Results: BMDJ were detected in all patients, with 4.42 ± 2.75 BMDJ findings per patient. RANTES/CCL5 levels were significantly reduced by any treatment compared with no treatment (p < 0.001; effect size d = 0.90). This effect was most pronounced in the BMDJ surgery group (p < 0.001; effect size d = 1.30). In contrast, serum RANTES/CCL5 concentrations increased further in untreated patients. The mean time between pre- and post-treatment RANTES/CCL5 measurements was 22.86 ± 19.36 weeks, with no correlation with RANTES/CCL5 levels in any intervention group or in the full sample (p = 0.104). BMDJ surgery, tooth extraction, and root canal treatment significantly reduce serum RANTES/CCL5 concentrations in patients with BMDJ, with surgery being the most beneficial. Further research is needed to establish regular RANTES/CCL5 assessments as part of improved diagnosis, monitoring, and evaluation of treatment success in patients with BMDJ.

Reduction of Inflammatory RANTES/CCL5 Serum Levels by Surgery in Patients with Bone Marrow Defects of the Jawbone. · Clin Cosmet Investig Dent 2023
Money for the studynot stated
Do the authors have ties to companies?no — the authors say so
Did a manufacturer help with the study?NO
Type of studyobservation of people
Participants113

“Not stated” does not mean nobody paid — the database does not always record it.

Samples of altered tissue from areas around surgical sites and other regions showed significantly elevated inflammatory markers compared with healthy bone.

Aim of the study: This research explores whether common and widespread dental procedures (DP), such as root filling (RF) and wisdom tooth (WT) removal, contribute to chronic inflammation in the jawbone. In performing these procedures, dentists may unknowingly cause defective wound healing in the jawbone, without recognizing its connection to inflammatory mediators or the possibility that it could be a hidden cause of chronic systemic diseases (SYD).

Results: All fatty necrotic and osteolytic jawbone (FDOJ) samples showed regulated on activation, normal T-cell expressed and secreted (RANTES) and fibroblast growth factor (FGF)-2 as the only extremely overexpressed cytokines. FDOJ groups showed a mean 30-fold overexpression of RANTES and a 20-fold overexpression of FGF-2 compared with healthy controls. Since RANTES is discussed in the literature as a possible contributor to inflammatory diseases and may have cancer-promoting effects, we hypothesize that FDOJ in areas of improper and incomplete wound healing in the jawbone may act as hyperactivated signaling pathways while serving as an unknown source of “silent inflammation.” Given the wide range of immune diseases associated with RANTES, treating FDOJ may help predict or assess the prognosis of many potential individual outcomes.

Chemokine RANTES/CCL5 as an unknown link between wound healing in the jawbone and systemic disease: is prediction and tailored treatments in the horizon? · EPMA J 2015
Money for the studynot stated
Do the authors have ties to companies?not stated
Did a manufacturer help with the study?unknown
Type of studyobservation of people

“Not stated” does not mean nobody paid — the database does not always record it.

In patients with facial pain or neuralgia, the bone samples studied showed elevated RANTES/CCL5 levels, although a causal link with pain remains a hypothesis.

Aim of the study: Introduction. This study explores the possible causal role of chronic subclinical inflammation in the jawbone of patients with atypical facial pain (AFP) and trigeminal neuralgia (TRN) in the local overexpression of the chemokine regulated on activation and normal T-cell expressed and secreted (RANTES/C-C motif ligand 5, CCL5).

Results: The FDOJ group with AFP/TRN showed a mean 30-fold overexpression of RANTES compared with healthy jawbones. Conclusions. To the best of our knowledge, no other research has identified RANTES overexpression in silently inflamed jawbones as a possible cause of AFP/TRN. We therefore hypothesize that surgical removal of FDOJ may reduce RANTES signaling pathways in neurons and help relieve chronic neurological pain in patients with AFP/TRN.

Peripheral Neuropathic Facial/Trigeminal Pain and RANTES/CCL5 in Jawbone Cavitation. · Evid Based Complement Alternat Med 2015
Money for the studynot stated
Do the authors have ties to companies?no — the authors say so
Did a manufacturer help with the study?NO
Type of studyobservation of people
Participants15

“Not stated” does not mean nobody paid — the database does not always record it.

Jawbone lesion samples showed excess RANTES/CCL5, and blood levels decreased after surgery in the patients studied.

Aim of the study: The role of signaling pathways in cell-to-cell communication during cancer progression has become a crucial area of study. The chemokine RANTES (regulated upon activation, normal T-cell expressed and secreted), also known as chemokine C-C motif ligand 5 (CCL5) (R/C), is a protein that cancer research focuses on because of its link to aggressive cancer development.

Results: Strong overexpression of R/C was seen in all FDOJ samples. Serum R/C levels were statistically lower after FDOJ surgery (p=0.0241). The authors proposed the hypothesis that FDOJ may trigger BC progression through R/C overexpression, and therefore encourage clinicians to raise awareness of FDOJ throughout the dental and medical communities in cases of BC.

Jawbone Cavitation Expressed RANTES/CCL5: Case Studies Linking Silent Inflammation in the Jawbone with Epistemology of Breast Cancer. · Breast Cancer (Dove Med Press) 2021
Money for the studynot stated
Do the authors have ties to companies?yes — the authors reported it
Did a manufacturer help with the study?YES
Type of studyobservation of people

“Not stated” does not mean nobody paid — the database does not always record it.

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