Herbs and plantsCandytuft—a garden-bed flower once thought to treat ulcers and intestinal problems?
- Henryk Różański — Ubiorek – Iberis w praktycznej fitoterapii.
- Henryk Różański — Pierwszy krok EFSA – European Food Safety Authority do zniszczenia zielarstwa i ziołolecznictwa europejskich narodów pod przykrywką badań naukowych i pseudo-troską o bezpieczeństwo obywateli.
- Iberis amara L. and Iberogast--results of a systematic review concerning functional dyspepsia. · J Herb Pharmacother 2004
- STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. · Am J Gastroenterol 2007
- [Iberogast: a modern phytotherapeutic combined herbal drug for the treatment of functional disorders of the gastrointestinal tract (dyspepsia, irritable bowel syndrome)--from phytomedicine to "evidence based phytotherapy." A systematic review]. · Forsch Komplementarmed Klass Naturheilkd 2002
- Spasmolytic and tonic effect of Iberogast (STW 5) in intestinal smooth muscle. · Phytomedicine 2006
It also lists uses for ulcers, inflammatory bowel conditions, and urinary and respiratory complaints.
- It attributes different uses to the infusion, tincture, and fresh herb; dried herb loses many of its medicinal properties.
- Candytuft was also listed among plants intended for making medicines, not food or dietary supplements.
What the authors write
The candytuft infusion is described as being used for problems with bile and pancreatic juice secretion, fat digestion, scanty urination, and intestinal and urinary tract complaints.
Fresh candytuft herb combined with other plants is described as being used for peptic ulcers, reflux, heartburn, and intestinal inflammation.
Candytuft tincture is described as being used for respiratory conditions in combination with other tinctures.
Candytuft tincture is described as useful for urinary tract infections, in combination with other tinctures.
For peptic ulcers, candytuft tincture is described as being combined with other tinctures.
Drops containing bitter candytuft extract are described as being recommended for digestive complaints.
For the listed liver problems, combining aqueous extracts of fresh candytuft herb with preparations from other plants is described.
Several candytuft species, including bitter and evergreen candytuft, are mentioned for medicinal use.
Candytuft was listed among plants considered strictly medicinal and intended for making medicines.
Research from PubMed · Europe PMC
We selected 4 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 11.
The review found that Iberogast, a product containing candytuft, reduced symptoms of functional dyspepsia.
Aim of the study: A systematic review of the efficacy and tolerability of the herbal combination Iberogast (Iberis amara planta totalis, Chelidonii herba, Cardui mariae fructus, Melissae folium, Carvi fructus, Liquiritiae radix, Angelicae radix, Matricariae flos, Menthae piperitae folium) was conducted in patients with functional dyspepsia.
Results: A systematic review of the efficacy and tolerability of the herbal combination Iberogast (Iberis amara planta totalis, Chelidonii herba, Cardui mariae fructus, Melissae folium, Carvi fructus, Liquiritiae radix, Angelicae radix, Matricariae flos, Menthae piperitae folium) was conducted in patients with functional dyspepsia. Three placebo-controlled trials and one reference-controlled trial showed a statistically significant and therapeutically relevant reduction in gastrointestinal symptom scores in 595 patients. Therapeutic efficacy was also found in one observational study (2267 patients). Based on the available evidence, Iberogast seems to be an effective herbal preparation for reducing dyspepsia symptoms, without central nervous system side effects.
“Not stated” does not mean nobody paid — the database does not always record it.
In a study, the product STW 5, which contains candytuft, improved symptoms of functional dyspepsia more than placebo.
Aim of the study: Functional dyspepsia (FD) is a complex condition with a variety of symptoms in the upper abdomen. There is currently no standard treatment for FD. This multicenter, placebo-controlled, double-blind study evaluated the efficacy and tolerability of the herbal medicine STW 5, which mainly contains a fresh plant extract of Iberis amara.
Results: A total of 315 patients were included in the safety population. Of these, 158 were treated with STW 5 and 157 with placebo. The intention-to-treat population comprised 308 patients. The number of dropouts was similar in both groups. Gastrointestinal symptoms improved during the treatment period. The STW 5 group improved by 6.9+/-4.8 points by day 56, compared with 5.9+/-4.3 in the placebo group (P<0.05). H. pylori did not affect the results. Drug tolerability and safety were similar in both groups. This placebo-controlled study, with an 8-week treatment period, documents the efficacy of STW 5 in FD.
“Not stated” does not mean nobody paid — the database does not always record it.
The review indicated that a candytuft-containing product is used for functional dyspepsia and irritable bowel syndrome.
Aim of the study: Iberogast is a complex herbal preparation. As a fixed drug combination (9 constituents), it is composed of a fresh plant extract of Iberis amara and extracts of 8 other dried herbal drugs (Chelidonii herba, Cardui mariae fructus, Melissae folium, Carvi fructus, Liquiritiae radix, Angelicae radix, Matricariae flos, Menthae piperitae folium).
Results: Two trials comparing Iberogast with the prokinetic drugs metoclopramide and cisapride found that the herbal preparation and the prokinetic drugs had comparable effectiveness in treating dyspepsia. Adverse events were rare and, in frequency and type, were in some cases the same as those seen with placebo. Another advantage of Iberogast is that it acts only on the gastrointestinal tract and the enteric nervous system, not the central nervous system. Because of its distinctive dual action, clinically proven effectiveness, and good tolerability, Iberogast may be a first-choice medicine for functional gastrointestinal disorders and their related symptoms.
“Not stated” does not mean nobody paid — the database does not always record it.
A laboratory study suggests that candytuft may support the action of a preparation that relieves spasms and regulates intestinal muscle tone.
Aim of the study: STW 5 (Iberogast) is a fixed combination of nine medicinal plant extracts that is effective in treating functional dyspepsia and irritable bowel syndrome.
Results: This was also true when STW 5 was used. An antispasmodic effect of STW 5 was also observed in the duodenum, jejunum, and colon. These data are the first to show not only the antispasmodic effects of STW 5 and its component extracts on intestinal muscle, but also the tonic effects of STW 5, through its Iberis amara extract, on relaxed intestinal muscle. Thus, pharmacological evidence suggests a dual-action principle and may partly explain the clinically observed therapeutic efficacy of STW 5 (Iberogast) for both low-tone and spasmodic motility symptoms of functional dyspepsia and irritable bowel syndrome.
“Not stated” does not mean nobody paid — the database does not always record it.
Pisaczek does not judge who is right. It shows what was written and where to read it. Every sentence above has its source.