DiseasesHigh blood pressure — is salt to blame, or a lack of potassium?
- Jerzy Zięba — O soli
- Henryk Różański — Siarczan potasu – Kalium sulfuricum jako lek w dawnej medycynie.
- Henryk Różański — Zaburzenia gospodarki magnezowej.
- Prof. Klaus F. Kopp — Das Bikarbonat-Mangel-Syndrom (BDS): Professor Dr. med. Klaus F. Kopp
- Prof. Klaus F. Kopp — The Bicarbonate-Deficiency-Syndrome (BDS): Professor Dr. med. Klaus F. Kopp
- Dietary salt intake and cardiovascular outcomes: an umbrella review of meta-analyses and dose-response evidence. · Ann Med 2025
- Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials. · J Am Heart Assoc 2020
- Sodium-to-potassium ratio and blood pressure, hypertension, and related factors. · Adv Nutr 2014
- Nonpharmacologic Interventions for Reducing Blood Pressure in Adults With Prehypertension to Established Hypertension. · J Am Heart Assoc 2020
- Potassium and Hypertension: A State-of-the-Art Review. · Am J Hypertens 2024
- Orthomolecular Medicine News Service — Vitamin C Questions: Answered
There is no single agreed answer: Jerzy Zięba rejects salt as a cause of high blood pressure, while Prof. Klaus F. Kopp points to a bicarbonate deficiency.
- Prof. Klaus F. Kopp also warns against excessive salt intake in people with high blood pressure.
- Henryk Różański describes a short-term drop in blood pressure after potassium sulfate, but does not identify a lack of potassium as a cause of high blood pressure.
- Henryk Różański links low potassium levels with magnesium deficiency and lists high blood pressure among the symptoms of long-term magnesium deficiency.
What the authors write
Eating salt does not contribute to high blood pressure; in fact, properly used salt is said to lower blood pressure.
Low-salt diets are harmful to people.
In the author's tests, potassium sulfate caused a drop in blood pressure that he described as noticeable but short-lived.
Magnesium deficiency may be accompanied by low potassium levels, and high blood pressure is listed among the symptoms of long-term magnesium deficiency.
Prof. Klaus F. Kopp attributes high blood pressure to a bicarbonate deficiency and claims that replenishing bicarbonate can treat it effectively.
Prof. Klaus F. Kopp notes that salt can be harmful in certain situations, while sodium bicarbonate at ordinary concentrations may be beneficial.
Prof. Klaus F. Kopp writes that people with high blood pressure should not eat too much salt.
Research from PubMed · Europe PMC
We selected 5 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 7 827.
A review found that sodium restriction is associated with lower blood pressure, while high salt intake is associated with a greater risk of high blood pressure.
Aim of the study: Excessive salt intake is a known risk factor for cardiovascular disease (CVD), but the health impacts of both high and low sodium intake remain debated. This study synthesizes meta-analytic evidence on dietary salt intake and cardiovascular outcomes, including subgroup and dose-response analyses.
Results: Twenty-one meta-analyses comprising 91 outcomes were included. Low sodium intake was associated with reduced risks of CVD mortality (RR = 0.83, 95% CI: 0.73-0.95), stroke mortality (RR = 0.74, 95% CI: 0.57-0.95), and all-cause mortality (RR = 0.88, 95% CI: 0.82-0.93), as well as lower systolic blood pressure (MD = -3.39 mmHg) and diastolic blood pressure (MD = -1.54 mmHg), improved vascular elasticity, and increased heart rate. Urinary sodium excretion and the Na/K ratio decreased, while urinary potassium and calcium, and serum potassium increased. No adverse effects on lipid profiles were observed. High salt intake was associated with increased risks of CVD (RR = 1.13, 95% CI: 1.06-1.20), hypertension (OR = 1.33, 95% CI: 1.24-1.42), stroke (OR = 1.34, 95% CI: 1.19-1.51), and stroke mortality (OR = 1.40, 95% CI: 1.21-1.63). Each 1 g/day increase in sodium raised systolic blood pressure by 0.60 mmHg and CVD and stroke risks by 4% and 6%, respectively.
“Not stated” does not mean nobody paid — the database does not always record it.
A meta-analysis found that potassium supplementation lowers blood pressure, especially in people with hypertension and those with higher sodium intake, although the relationship was not linear.
Aim of the study: Background: Epidemiologic studies, including trials, suggest an association between potassium intake and blood pressure (BP). However, the strength and shape of this relationship are uncertain.
Results: The BP-lowering effects of potassium supplementation were stronger in participants with hypertension and at higher levels of sodium intake. An increase in BP with high potassium excretion was noted in participants with hypertension treated with antihypertensive drugs, but not in their untreated counterparts. Conclusions: We identified a nonlinear relationship between potassium intake and both systolic and diastolic BP, although estimates of the BP effects of high potassium intakes should be interpreted with caution because few trials were available. Our findings indicate that adequate potassium intake is desirable for achieving a lower BP level, but suggest that excessive potassium supplementation should be avoided, particularly in specific subgroups.
“Not stated” does not mean nobody paid — the database does not always record it.
A review found that the sodium-to-potassium ratio was more strongly associated with blood pressure than sodium or potassium alone in adults with hypertension.
Aim of the study: The potential cost-effectiveness and feasibility of dietary interventions aimed at reducing hypertension risk are of considerable interest and importance in public health. In particular, the effectiveness of restricted sodium or increased potassium intake in reducing hypertension risk has been demonstrated in clinical and observational research.
Results: The main findings show that, among the randomized controlled trials reviewed, the sodium-to-potassium ratio appears to be more strongly associated with blood pressure outcomes than either sodium or potassium alone in adults with hypertension. Recent data from the observational studies reviewed provide further support for the sodium-to-potassium ratio as a better measure than sodium or potassium alone when assessing blood pressure outcomes and new cases of hypertension. It remains unclear whether this is true in people with normal blood pressure and in children, or for related outcomes including the renin-angiotensin system, arterial stiffness, the augmentation index, and endothelial dysfunction. Further research in these groups is warranted.
“Not stated” does not mean nobody paid — the database does not always record it.
A meta-analysis found that the DASH diet lowers blood pressure, and evidence also points to benefits from salt with less sodium and more potassium.
Aim of the study: Background: Nonpharmacologic interventions that modify lifestyle can lower blood pressure (BP) and have been assessed in numerous randomized controlled trials and pairwise meta-analyses. It is still unclear which intervention would be most effective.
Results: For patients with hypertension, moderate- to high-quality evidence suggested that the listed interventions (except comprehensive lifestyle modification) were associated with greater reductions in systolic and diastolic BP than usual care; salt restriction was also effective in lowering both systolic and diastolic BP. Among overweight and obese participants, a low-calorie diet and a low-calorie diet plus exercise could lower BP more than exercise alone. Conclusions: DASH may be the most effective intervention for lowering BP in adults with prehypertension through to established hypertension. Aerobic exercise, isometric training, low-sodium, high-potassium salt, comprehensive lifestyle modification, salt restriction, breathing control, meditation, and a low-calorie diet also have clear effects on reducing BP.
“Not stated” does not mean nobody paid — the database does not always record it.
A review found that increasing potassium may lower blood pressure, and potassium-enriched salt may also reduce the risk of stroke and cardiovascular death.
Aim of the study: Hypertension is the single most important modifiable risk factor for cardiovascular morbidity and mortality worldwide. Nonpharmacologic interventions, particularly dietary changes, have been shown to lower blood pressure (BP) and reduce hypertension-related cardiovascular events.
Results: Meanwhile, increasing dietary potassium intake has remained on the sidelines, despite similar BP-lowering effects. New research reveals a potential mechanism of action, explaining its effect on sodium excretion through the potassium switch effect. Additionally, potassium-substituted salt has been shown not only to reduce BP, but also to reduce the risk of stroke and cardiovascular mortality. Based on these data, we argue that the focus on dietary modification should shift from sodium alone to both sodium and potassium, with an emphasis on strategies that can be easily implemented in clinical practice.
“Not stated” does not mean nobody paid — the database does not always record it.
Perspectives and opinion materials
The content below presents the authors’ opinions, interpretations and hypotheses. It is not treated as equal to scientific studies and systematic reviews.
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