DiseasesLyme disease — can nature offer hope where antibiotics fail?
- Henryk Różański — Borelioza – Borreliosis – fitoterapia cz. III i trochę narzekania
- Henryk Różański — Borelioza – Borreliosis – fitoterapia, cz. IV
- Supplementary management of chronic Lyme disease with Pycnogenol®. · Minerva Med 2025
- Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. · Front Med (Lausanne) 2020
- Plantago major and Plantago lanceolata Exhibit Antioxidant and Borrelia burgdorferi Inhibiting Activities. · Int J Mol Sci 2024
- The anti-borreliae efficacy of phytochemicals and micronutrients: an update. · Ther Adv Infect Dis 2016
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It mentions cat’s claw, prepared as an infusion by boiling 5–6 g of the herb in water.
- It also recommends common teasel as an alcoholic extract or tincture, taken three times a day.
- It also mentions wormwood and echinacea as extracts or tinctures, and echinacea for topical use as well.
What the authors write
An alternative method of treating Lyme disease was described as using preparations of mineral, animal, and plant origin.
Cat’s claw is prepared as an infusion by boiling 5–6 g of the herb for five minutes in 220 ml of water.
Teasel extract is prepared by pouring hot vodka over fresh root or leaves, then taking 10 ml three times a day.
Teasel tincture is described as a preparation made from dried root or leaves, taken in 10 ml doses three times a day.
Echinacea is described as a tincture or extract taken in 5 ml doses three times a day, and also as a topical treatment for skin lesions.
Research from PubMed · Europe PMC
We selected 4 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 19.
In a small study, adding Pycnogenol to standard care was associated with fewer symptoms after six months than standard care alone.
Aim of the study: The aim of this pilot supplement registry study was to investigate the efficacy of the anti-inflammatory supplement Pycnogenol® in subjects with history of Lyme disease and persistent symptoms with no active bacteria present (Stage 2 and 3 of Lyme disease), on the reduction of inflammation and the relieve of the main symptoms. There is currently no specific treatment for this condition.
Results: Forty subjects with history of Lyme Disease and persistent symptoms completed the study: 20 in the Pycnogenol® group, 20 in the control group. No side effects from the supplementation were observed. The tolerability was optimal as no supplemented subject had to stop management and compliance was optimal with 97% of the Pycnogenol® capsules correctly used. The two groups were comparable for sex, age distribution and for their main clinical findings and signs/symptoms at inclusion. During the study, corticosteroids at low dose were used on demand in 10% of subjects using Pycnogenol® and significantly more, in 45% of the control patients (P<0.05). After 6 months, the number of patients experiencing symptoms was significantly lower in the Pycnogenol® group compared to the control group across all symptoms (P<0.05). After 6 months, the intensity of all symptoms in the Pycnogenol® group, was significantly lower, according to the scores in comparison with the control group (P<0.05).
“Not stated” does not mean nobody paid — the database does not always record it.
In a laboratory study, seven plant extracts showed activity against non-growing forms of Borrelia burgdorferi.
Aim of the study: Lyme disease is the most common vector-borne disease in the US and Europe. Although the current recommended Lyme antibiotic treatment is effective for the majority of Lyme disease patients, about 10-20% of patients continue to suffer from persisting symptoms.
Results: burgdorferi stationary phase cells as many spirochetes were visible after 21-day subculture. Further studies are needed to identify the active constituents of the effective botanicals and evaluate their combinations for more effective eradication of B. burgdorferi in vitro and in vivo. The implications of these findings for improving treatment of persistent Lyme disease are discussed.
“Not stated” does not mean nobody paid — the database does not always record it.
In a laboratory study, extracts from two plantain species inhibited Borrelia burgdorferi, and the most effective reduced bacterial viability to 15%.
Aim of the study: Lyme disease, caused by Borrelia burgdorferi sensu lato infection, is the most widespread vector-borne illness in the Northern Hemisphere. Unfortunately, using targeted antibiotic therapy is often an ineffective cure.
Results: burgdorferi inhibiting activity of the extracts was tested on stationary-phase B. burgdorferi culture and its biofilm fraction. All extracts showed antibacterial activity, with the most effective lowering the residual bacterial viability down to 15%. Moreover, the extracts prepared from the leaves of each plant additionally demonstrated biofilm inhibiting properties, reducing its formation by 30%.
“Not stated” does not mean nobody paid — the database does not always record it.
The review indicates that several natural compounds showed activity against Borrelia, but does not prove that they are effective treatments in humans.
Aim of the study: Naturally occurring substances have been used for centuries to fight against various pathogens. They serve as a source for new chemical entities or provide options to already existing therapeutics.
Results: While there is an increasing interest in studying antimicrobial properties of naturally derived agents, little is known about their effects against Borrelia burgdorferi sensu lato, the causative pathogens of Lyme disease. A better understanding of this aspect could advance knowledge about pathophysiology of these bacteria and help improve the efficacy of current approaches against Lyme disease. Here, we review all naturally occurring substances scientifically evaluated to date, including plant extracts, their metabolites, and micronutrients, against vegetative (spirochetes) and latent (rounded bodies, biofilm) forms of Borrelia sp. This summary reveals the potent anti-borreliae activity of several of these natural compounds indicating their potential in enhancing the efficacy of current treatments for Lyme disease, and offering new options to already existing therapeutic regiments.
“Not stated” does not mean nobody paid — the database does not always record it.
Perspectives and opinion materials
The content below presents the authors’ opinions, interpretations and hypotheses. It is not treated as equal to scientific studies and systematic reviews.
Pisaczek does not judge who is right. It shows what was written and where to read it. Every sentence above has its source.