Herbs and plantsLycopus — a forgotten herb for an overactive thyroid?
- Henryk Różański — Lycopus europaeus L. – karbieniec w leczeniu tarczycy
- Henryk Różański — Fitoterapia choroby Hashimoto, cz. II
- [Improvement of symptoms in mild hyperthyroidism with an extract of Lycopus europaeus (Thyreogutt® mono)]. · Wien Med Wochenschr 2013
- Lycopus europaeus (Gypsywort): effects on the thyroidal parameters and symptoms associated with thyroid function. · Phytomedicine 2008
- Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats. · Life Sci 2006
- Endocrine effects of Lycopus europaeus L. following oral application. · Arzneimittelforschung 1994
Henryk Różański says that Lycopus suppresses the production of thyroid-stimulating hormone and is used to treat an overactive thyroid.
- According to him, it may also reduce nervous agitation and thyroid-related heart palpitations.
- He lists Lycopus herb among natural remedies that suppress thyroid activity in hyperthyroidism associated with Hashimoto’s disease.
- He recommends monitoring hormone levels, starting with low doses, and increasing them gradually.
What the authors write
Lycopus is said to suppress the production of thyroid-stimulating hormone and to be used to treat an overactive thyroid.
Lycopus may reduce nervous agitation and thyroid-related heart palpitations.
For an overactive thyroid associated with Hashimoto’s disease, Henryk Różański lists Lycopus herb among natural remedies that suppress thyroid activity.
Henryk Różański recommends monitoring hormone levels while using Lycopus.
Henryk Różański recommends starting with low doses and increasing them gradually.
Henryk Różański warns against stopping treatment suddenly and recommends reducing doses gradually.
Research from PubMed · Europe PMC
We selected 4 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 7.
In an observational study, Lycopus extract was associated with improvement in some people with mild hyperthyroidism, more often than no treatment.
Aim of the study: Extracts of Lycopus europaeus are used clinically to control vegetative and irritative symptoms in mild hyperthyroidism. This study assessed the effects and safety of an extract of Lycopus europaeus (Thyreogutt® mono tablets or drops) in a general practice setting.
Results: A total of 403 patients with mild symptomatic hyperthyroidism were observed. The prospective assessment included 146 patients, the retrospective assessment 171 patients, and the control group 86 untreated patients. The response rate was 72.6% in the prospective assessment and 96.5% in the retrospective assessment, compared with 41.2% in the untreated control group. No adverse events were reported. The Lycopus europaeus extract was well tolerated and was associated with a statistically significant and clinically relevant improvement in symptoms of mild hyperthyroidism. Improvement was markedly greater in both Thyreogutt® mono groups than in the control group.
“Not stated” does not mean nobody paid — the database does not always record it.
In an open study of people with mild hyperthyroidism, using Lycopus reduced some symptoms, and the authors considered the results positive.
Aim of the study: The aim of the prospective, two-arm, open study was to examine the effect of Lycopi europaei herba on thyroid function and associated symptoms during a 3-month follow-up period. The study population consisted of patients with a basal TSH <1.0 mU/l and symptoms associated with hyperthyroidism.
Results: Symptoms specific to the thyroid gland were reduced, such as an increased heart rate in the morning. The Lycopus europaeus preparation was well tolerated. These findings confirm positive effects of Lycopus europaeus in mild forms of hyperthyroidism.
“Not stated” does not mean nobody paid — the database does not always record it.
In rats with thyroxine-induced hyperthyroidism, Lycopus extract lowered heart rate and blood pressure and alleviated heart enlargement.
Aim of the study: Extracts from the plant Lycopus europaeus L. are traditionally used in mild forms of hyperthyroidism.
Results: Lycopus extract and atenolol reduced the increased heart rate and blood pressure. Both treatments significantly alleviated cardiac hypertrophy. Lycopus extract and the beta-blocking agent significantly reduced beta-adrenoceptor density in heart tissue, with almost equal efficacy. Although the mode of action remains unclear, these organ-specific anti-T4 effects may be of practical interest, for example in patients with latent hyperthyroidism.
“Not stated” does not mean nobody paid — the database does not always record it.
In rats, oral administration of Lycopus extract lowered T3, T4, and TSH levels.
Aim of the study: Lycopus extracts are used in folk medicine to treat symptoms of hyperthyroidism. Experimental studies have confirmed various effects on the pituitary-thyroid system as well as the pituitary-gonadal system.
Results: A marked reduction in T4 and thyroid-stimulating hormone (TSH) concentrations was observed 24 hours after the test solution was administered by gavage. The decrease in luteinizing hormone (LH), as well as the decrease in TSH despite reduced T4 and T3 levels, indicates that the plant extract acts centrally. Differences in biological activity depending on the route of administration may be explained, for example, by differences in the absorption of plant constituents.
“Not stated” does not mean nobody paid — the database does not always record it.
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