DiseasesHigh blood pressure pills — do they treat the cause or just the reading?
Sources: 8 · Article: 7 883 characters
Andrzej Frydrychowski points to the blocking of angiotensin receptors in blood vessels and argues for acting at a higher level of regulation.
- Prof. Klaus F. Kopp says that medicines usually block the action of hormones but do not correct a bicarbonate deficiency; in his view, replacing bicarbonate can lower blood pressure.
- Jerzy Jaśkowski notes that blood pressure measurement is used to assess a patient's condition, and that a proper measurement should be taken on the arm.
What the authors write
Jerzy Jaśkowski
Blood pressure measurement is used to assess a patient's condition, and an arm measurement is identified as the proper method.
„The formula from this law allows us to assess a patient's condition by measuring blood pressure. However, we must remember that only an arm measurement is proper. Wrist measurements, which are easier to take, provide only an approximate value. To monitor a patient's blood pressure, we should also take measurements on the arm, at different times of day.”Wzór z tego prawa pozwala na ocenę stanu chorego poprzez pomiar ciśnienia krwi. Musimy jednak pamiętać, że tylko pomiar ramienny jest prawidłowy. Pomiary nadgarstkowe, łatwiejsze do przeprowadzenia, dają tylko wartość orientacyjną. W celu kontrolowania u chorego wartości ciśnienia powinniśmy dokonywać pomiaru ciśnienia także na ramieniu, w dodatku o różnej porze dnia.
Andrzej Frydrychowski
The medicines used block angiotensin receptors in blood vessels, while the author identifies a higher level of regulation as the place where a therapeutic effect should be achieved.
„A therapeutic effect would be achieved at the highest level of regulation (for example, the vasomotor centers), rather than at the final, effector level of treatment—that is, by blocking angiotensin receptors in blood vessels with the medicines used. Restoring impaired autoregulation could naturally help reverse many disease-related changes and, in many cases, eliminate or greatly reduce the use of medicines.”Efekt leczniczy uzyskalibyśmy na najwyższym piętrze regulacji (np. ośrodki naczynioruchowe), a nie ostatnim piętrze leczenia (efektorowym), to jest na poziomie blokady receptorów angiotensyny w naczyniach krwionośnych poprzez stosowane leki. Przywrócenie zaburzonej autoregulacji mogłoby przyczynić się w naturalny sposób do cofnięcia wielu zmian chorobowych i w wielu przypadkach wyeliminować lub znacznie zmniejszyć stosowanie leków.
Andrzej Frydrychowski
According to the author, restoring impaired autoregulation could reverse some changes and reduce the need for medicines.
„Restoring impaired autoregulation could naturally help reverse many disease-related changes and, in many cases, eliminate or greatly reduce the use of medicines.
The text comes from excerpts of a book on auriculotherapy, in whose preparation the doctor took part.”Przywrócenie zaburzonej autoregulacji mogłoby przyczynić się w naturalny sposób do cofnięcia wielu zmian chorobowych i w wielu przypadkach wyeliminować lub znacznie zmniejszyć stosowanie leków.
Tekst pochodzi z fragmentów książki o aurikuloterapii, w której opracowaniu brał udział lek.
Prof. Klaus F. Kopp
Prof. Klaus F. Kopp says that typical medicines block hormones associated with high blood pressure but do not treat the bicarbonate deficiency he points to.
„The prescribed medicine therefore usually comprises only pharmacological hormone antagonists against the hormones of the renin-angiotensin-aldosterone group. Unfortunately, the bicarbonate deficit is never treated. Bicarbonate supplementation is usually very effective in lowering blood pressure into the normal range, provided that no significant secondary damage from hypertension is already present in the body, e.g.”The prescribed medicine therefore usually comprises only the pharmacological hormone-antagonists against the hormones of the renin-angiotensin-aldosteron-group Unfortunately, the bicarbonate-deficit is never being treated. Substitution of bicarbonate is usually very effective in lowering the blood pressure into the normal range provided that no significant secondary damages of hypertension are already present in the body e.g.
Prof. Klaus F. Kopp
Prof. Klaus F. Kopp presents bicarbonate deficiency as an unresolved cause and bicarbonate replacement as a way to treat hypertension.
„Only the bicarbonate deficiency is not corrected anywhere. Sodium bicarbonate would be the physiologically most effective vasodilating substance. In fact, consistent bicarbonate supplementation, with lasting replenishment of bicarbonate stores, can effectively treat hypertension; this brings about a state of “alkalotic volume contraction.””Nur der Bikarbonat-Mangel wird nirgendwo beseitigt. Natrium-Bikarbonat wäre dabei die physiologisch am besten wirkende vasodilatatorische Substanz. Tatsächlich gelingt es durch konsequente Bikarbonat-Substitution mit dauerhafter Sättigung der Bikarbonat-Speicher eine Hypertonie wirksam zu therapieren, der Zustand der „alcalotic volume-contractions“ wird hierdurch herbeigeführt.
Research from PubMed · Europe PMC
We selected 1 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 73 992.
In pregnant women with hypertension, labetalol and methyldopa reduced the risk of severe hypertension compared with placebo or no treatment.
Aim of the study: When considering the safety and effectiveness of oral antihypertensive agents for treating hypertensive disorders of pregnancy, no preference can be stated among the 3 agents currently available. Therefore, this systematic review and network meta-analysis aims to determine the effects of antenatal treatment with methyldopa, labetalol, or nifedipine for hypertensive disorders of pregnancy on maternal or fetal/neonatal morbidity and mortality.
Results: Twenty-three trials (3989 women) were included in our network meta-analysis, with overall low-to-moderate quality. Compared with placebo/no treatment, labetalol and methyldopa significantly reduced the incidence of severe hypertension (8 studies; relative risk 0.20 [95% confidence interval 0.09–0.48] and 0.44 [0.20–0.99], respectively). In the network meta-analysis, labetalol compared with nifedipine was associated with a reduction in preeclampsia (relative risk, 0.50 [0.28–0.87]; 15 studies) and preterm birth (relative risk, 0.68 [0.52–0.90]; 14 studies). No significant differences were found for any of the other outcomes of interest. In direct comparisons of the oral antihypertensive agents currently available, no significant differences were found in the primary outcome, severe hypertension, or in most of the secondary outcomes of interest.
Money for the studycompany or manufacturer · Achmea
Do the authors have ties to companies?not stated
Did a manufacturer help with the study?YES
Type of studycombined analysis of many studies (meta-analysis)
Participants3 989
“Not stated” does not mean nobody paid — the database does not always record it.
Perspectives and opinion materials
The content below presents the authors’ opinions, interpretations and hypotheses. It is not treated as equal to scientific studies and systematic reviews.
Orthomolecular Medicine News Service Opinion material
„[43] Endomyocardial biopsies have documented that heart muscle in congestive and hypertrophic cardiomyopathies has significantly depressed levels of both ATP and NAD. [44] Normal heart muscle has the highest NAD levels in the body. [45] Impaired energy metabolism has been identified in both congestive and hypertrophic cardiomyopathy. [46] Consistent with these findings, studies have shown that raising NAD levels can improve atherosclerosis as well as different forms of heart failure, including ischemic, hypertrophic, and congestive cardiomyopathies.”[43] Endomyocardial biopsies have documented that heart muscle in congestive and hypertrophic cardiomyopathies have significantly depressed levels of both ATP and NAD. [44] Normal heart muscle has the highest NAD levels in the body. [45] In both congestive and hypertrophic cardiomyopathy impaired energy metabolism has been identified. [46] Consistent with these findings, the elevation of NAD levels in different studies has been shown to improve atherosclerosis as well as different forms of heart failure, including ischemic, hypertrophic, and congestive cardiomyopathies.
Orthomolecular Medicine News Service Opinion material
„PMID: 22065968 Cicci G, Pirrelli A (1999) Red blood cell (RBC) deformability, RBC aggregability and tissue oxygenation in hypertension. Clinical Hemorheology and Microcirculation 21:169-177. PMID: 10711739 Eweas A, Alhossary A, Abdel-Moneim A (2021) Molecular docking reveals ivermectin and remdesivir as potential repurposed drugs against SARS-CoV-2. Frontiers in Microbiology 11:592908. PMID: 33746908 Fantini J, Di Scala C, Chahinian H, Yahi N (2020) Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection.”PMID: 22065968 Cicci G, Pirrelli A (1999) Red blood cell (RBC) deformability, RBC aggregability and tissue oxygenation in hypertension. Clinical Hemorheology and Microcirculation 21:169-177. PMID: 10711739 Eweas A, Alhossary A, Abdel-Moneim A (2021) Molecular docking reveals ivermectin and remdesivir as potential repurposed drugs against SARS-CoV-2. Frontiers in Microbiology 11:592908. PMID: 33746908 Fantini J, Di Scala C, Chahinian H, Yahi N (2020) Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection.
Orthomolecular Medicine News Service Opinion material
„A partial list of such agents includes the following: Lead Copper Iron Mercury Aluminum Cobalt/Chromium Cadmium Gold/Silver Chemotherapy COVID Spike protein Lead: In a 3-year-old girl with chronic lead poisoning, acute heart failure developed and was clinically reversed after four days of calcium EDTA chelation therapy. [16] Children who died from heart failure secondary to acute lead poisoning were documented to have microscopic findings of myocarditis. [17] Other studies have shown that lead targets the heart and vascular system.”A partial list of such agents includes the following: Lead Copper Iron Mercury Aluminum Cobalt/Chromium Cadmium Gold/Silver Chemotherapy COVID Spike protein Lead: In a 3-year-old girl with chronic lead poisoning, acute heart failure developed that was clinically reversed after four days of calcium EDTA chelation therapy. [16] Children who died from heart failure secondary to acute lead poisoning were documented to have the microscopic findings of myocarditis. [17] Lead has been shown in other studies to target the heart and the vascular system.
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