Diet and nutritionHeart and cholesterol — does a plate of vegetables work better than statins?
- Ewa Dąbrowska — Schorzenia i świadectwa
- Andrzej Frydrychowski — Wpływ statyn na nasze zdrowie
- Jerzy Jaśkowski — Statyny – lekarze o tym nie mówią
- Jerzy Jaśkowski — Czego nie wiemy o statynach?
- Thomas E. Levy — Dr. Thomas Levy
- The effect of combining plant sterols, soy protein, viscous fibers, and almonds in treating hypercholesterolemia. · Metabolism 2003
- Assessment of the longer-term effects of a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia. · Am J Clin Nutr 2006
- A Feasibility Assessment of Measuring Acceptance and Adherence to a Plant-Based (Vegan) Diet in a Cardiology Clinic. · Clin Cardiol 2026
- Orthomolecular Medicine News Service — VITAMIN LOWERS CHOLESTEROL
Jerzy Jaśkowski attributes muscle weakness, memory problems, and an increase in atherosclerotic changes in the arteries to statins.
- Ewa Dąbrowska describes a fruit-and-vegetable fast as a way to help improve insulin resistance, which is associated, among other things, with atherosclerosis and lipid disorders.
- Andrzej Frydrychowski links the effects of statins to disrupted synthesis of coenzyme Q10 and squalene, while Thomas E. Levy warns against their long-term use and very low cholesterol levels because of cancer risk.
What the authors write
A fruit-and-vegetable fast is intended to help improve insulin resistance, which underlies, among other things, atherosclerosis and lipid disorders.
Statins lower cholesterol by blocking the HMG-CoA pathway, which, according to Andrzej Frydrychowski, also disrupts the synthesis of coenzyme Q10 and squalene.
Jerzy Jaśkowski links statins to reduced production of coenzyme Q10, as well as muscle weakness and memory problems.
Jerzy Jaśkowski attributes an increase in atherosclerotic changes in the coronary arteries and aorta to statins, as well as a higher risk of cardiovascular complications in people with diabetes.
Jerzy Jaśkowski presents cholesterol as a substance the body needs and opposes lowering its levels with statins.
Thomas E. Levy warns against long-term statin use and very low cholesterol levels, linking them to an increased risk of cancer.
Research from PubMed · Europe PMC
We selected 3 studies with the best, positive results. This is a selection, not a full review of all research.
Total number of studies on this topic in PubMed: 21.
A diet combining plant sterols, soy protein, fiber, and almonds lowered LDL more than the control diet, but this study did not directly compare it with a statin.
Aim of the study: Reductions in low-density lipoprotein-cholesterol (LDL-C) result from diets containing almonds, or diets that are either low in saturated fat or high in viscous fibers, soy proteins, or plant sterols. We have therefore combined all of these interventions in a single diet (portfolio diet) to determine whether cholesterol reductions could be achieved of similar magnitude to those reported in recent statin trials which reduced cardiovascular events.
Results: The reductions in LDL-C and the LDL:HDL-C ratio were both significantly lower on the portfolio diet than on the control diet (P<.001 and P<.001, respectively). Mean weight loss was similar on test and control diets (1.0 kg and 0.9 kg, respectively). No difference was seen in blood pressure, HDL-C, serum triglycerides, lipoprotein(a) [Lp(a)], or homocysteine concentrations between diets. Combining a number of foods and food components in a single dietary portfolio may lower LDL-C similarly to statins and so increase the potential effectiveness of dietary therapy.
“Not stated” does not mean nobody paid — the database does not always record it.
After one year on the portfolio diet, LDL fell by an average of about 13%, and in some participants the reduction was comparable to results from their earlier statin trial.
Aim of the study: Cholesterol-lowering foods may be more effective when consumed as combinations rather than as single foods. Our aims were to determine the effectiveness of consuming a combination of cholesterol-lowering foods (dietary portfolio) under real-world conditions and to compare these results with published data from the same participants who had undergone 4-wk metabolic studies to compare the same dietary portfolio with the effects of a statin.
Results: At 3 mo and 1 y, mean (+/-SE) LDL-cholesterol reductions appeared stable at 14.0 +/- 1.6% (P < 0.001) and 12.8 +/- 2.0% (P < 0.001), respectively (n = 66). These reductions were less than those observed after the 1-mo metabolic diet and statin trials. Nevertheless, 31.8% of the participants (n = 21 of 66) had LDL-cholesterol reductions of >20% at 1 y (x +/- SE: -29.7 +/- 1.6%). The LDL-cholesterol reductions in this group were not significantly different from those seen after their respective metabolically controlled portfolio or statin treatments. A correlation was found between total dietary adherence and LDL-cholesterol change (r = -0.42, P < 0.001). Only 2 of the 26 participants with <55% compliance achieved LDL-cholesterol reductions >20% at 1 y.
“Not stated” does not mean nobody paid — the database does not always record it.
After 8 weeks on a plant-based diet, participants’ total cholesterol had decreased.
Aim of the study: Plant-based vegan diets (PBVDs) improve cardiometabolic risk markers, hence are recommended as an adjunct treatment by some cardiologists. To complete a service evaluation, practical measures of dietary adherence are required, and perceptions of patients need to be considered.
Results: Twenty patients completed the dietary assessment. After 8 weeks, 55% (n = 11) were classified as fully adherent to the PBVD. Mean score for the PBVD-S increased from 20.3 ± 8.7 at baseline to 38.9 ± 5.8 at Week 8. Mean total cholesterol (TC), body mass index (BMI), body mass, and waist circumference significantly decreased (p < 0.001) after 8 weeks on the PBVD. The PBVD-S satisfied the feasibility criteria of alignment with diet education and assessment of adherence. The PBVD was rated as either "moderately" or "extremely" acceptable by 80% of patients. The PBVD-S is a feasible option for assessing adherence and diet quality of a PBVD in a cardiology outpatient setting.
“Not stated” does not mean nobody paid — the database does not always record it.
Perspectives and opinion materials
The content below presents the authors’ opinions, interpretations and hypotheses. It is not treated as equal to scientific studies and systematic reviews.
Pisaczek does not judge who is right. It shows what was written and where to read it. Every sentence above has its source.